3,176 research outputs found
Security and Online learning: to protect or prohibit
The rapid development of online learning is opening up many new learning opportunities. Yet, with this increased potential come a myriad of risks. Usable security systems are essential as poor usability in security can result in excluding intended users while allowing sensitive data to be released to unacceptable recipients. This chapter presents findings concerned with usability for two security issues: authentication mechanisms and privacy. Usability issues such as memorability, feedback, guidance, context of use and concepts of information ownership are reviewed within various environments. This chapter also reviews the roots of these usability difficulties in the culture clash between the non-user-oriented perspective of security and the information exchange culture of the education domain. Finally an account is provided of how future systems can be developed which maintain security and yet are still usable
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"We muddle our way through": shared and distributed expertise in digital engagement with research
The use and availability of digital media is changing researchers' roles and simultaneously providing a route for a more engaging relationship with stakeholders throughout the research process. Although the digital realm has a profound influence on people's day-to-day lives, some researchers have not yet professionally embraced digital technologies. This paper arises from one aspect of a project exploring how university research and professional practices are evolving as researchers engage with stakeholders via digital media to create, share and represent knowledge together. Using researchers from the Open University (U.K.) as a case study, this paper reviews the extent to which they are developing multiple identities and functions in their engaged research through digital media
Preferences for Exposure Control of Power-Frequency Fields among Lay Opinion Leaders
The authors report on surveys, differing according to focus on remedial costs, of Pittsburgh-area adults indicating beliefs about possible health effects of electromagnetic fields and the acceptability of options for reducing or eliminating the potential impact
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Artistic participatory video-making for science engagement
This paper uses theatre to frame reflexive discussions on the use of participatory video making for science engagement. The ‘JuxtaLearn’ research project is presented as a case-study that focuses on performance concepts such as audience, purpose, improvisation or final production as a lens for supporting technology-enabled creative exploration. Three different approaches were taken to creative participatory video making processes: co-creation by learners, as a communication tool for researchers and as a public engagement tool. Differing expectations about the timing and aim of the research process created considerable debate among the research team regarding the control of and purpose of filmmaking. It was not the topic of debate within the film that was deemed controversial, but more who, when and in what ways these debates occurred. Theatrical and HCI concepts of audience, performance ownership, improvisation and storyboarding, boundary object creation, participation and boundary creatures are foci of debate within the project
Adolescent Attitudes Toward the Employment of Women
The past twenty-five years has brought about a substantial increase in the number of American women participating in the labor force. In 1940, approximately 12.8 million women were involved in employment outside the home; this was 25 percent of the total female population 14 years of age and over. By 1964, the number of employed women had doubled; there were then 25.8 million women workers. Out-of-the-home employment was actively engaging 37 percent of American women (7, p. 301). However, not only has there been an increase in the number of workers; there are also changes in the percent of women involved, the number of years a woman spends in active participation in the labor force, and in the work cycle of employed women
Proteases of the neutrophil membrane represent an alternative fibrinolytic pathway to that mediated by plasmin
The cellular components of the blood, which become associated with fibrin through specific cellular adhesive processes, play a significant role in the breakdown of fibrin. Fibrinolysis by elastase and cathepsin G, enzymes present within the azurophilic granules of the neutrophil, has previously been shown. Recent studies have demonstrated neutrophil-mediated fibrinogenolysis by a membrane-associated protease which suggests that proteases connected with the neutrophil membrane might also be capable of clot dissolution. Investigations showed that neutrophil-mediated clot lysis was effected by a membrane-associated serine protease that can be dissociated by SDS-PAGE to bands that migrate to apparent molecular weights of 501 kDa, 398 kDa, 316 kDa, 245 kDa and 209 kDa. This degradation was distinct from that produced by plasmin, neutrophil lysosomal enzymes and purified human neutrophil elastase and enhanced the action of plasmin in clot solubilization. Preincubation of neutrophils with monoclonal antibodies directed against the CD 11 c/CD 18 integrin was able to significantly inhibit neutrophil membrane-dependent fibrinolytic activity. Upregulation of enzyme activity occurred following association of fibrin substrate with the cell membrane and was dependent on the activation of cellular kinases, in particular protein kinase C. Fibrin products generated by neutrophil membrane proteolytic activity were found to possess biological activity. The low molecular weight peptides effected substantial inhibition of thrombin-induced platelet aggregation while the presence of the higher molecular weight material could partially overcome platelet-induced resistance to plasmic lysis. No modulation of platelet-mediated fibrin clot retraction was observed using these same fibrin products. Neutrophil lysosomal enzyme activity was shown to further degrade the end products of plasmic fibrin degradation into low molecular weight material, followed by reassembly of higher molecular weight products in a process dependent on calcium and factor XIII. The reformed products have a similar molecular weight to those produced by plasmic lysis of fibrin, as well as a putative crosslinked site. However, the isoelectric point of these reformed products indicates they are distinctly different from plasmin-derived fibrin products. These reassembled products were recognized by a monoclonal antibody raised against D-dimer. Processing by neutrophils of the end products of plasmic fibrin degradation may have the potential for modulating the immune response as well as compromising the predictive value of tests measuring D-dimer, used as a laboratory marker of a number of thromboembolic disorders encountered in clinical practice
Elis Gruffydd and Welsh identity in the sixteenth century.
In 1552, Welsh soldier and chronicler Elis Gruffydd (c.1490-c.1552) completed a 2500-folio manuscript, which is little known and rarely studied. Its obscurity belies its importance. This document can tell us much about Welsh opposition to Tudor policies in the British Isles, an often-overlooked subject; his experience as Europe transitioned from the Middle Ages to the Early Modern era; and writing as a form of resistance, a subject receiving little scholarly attention prior to the eighteenth and nineteenth centuries
Digital libraries' support for the user's information journey
The temporal elements of users' information requirements are a continually confounding aspect of digital library design. No sooner have users' needs been identified and supported than they change. This paper evaluates the changing information requirements of users through their 'information journey' in two different domains (health and academia). In-depth analysis of findings from interviews, focus groups and observations of 150 users have identified three stages to this journey: information initiation, facilitation (or gathering) and interpretation. The study shows that, although digital libraries are supporting aspects of users' information facilitation, there are still requirements for them to better support users' overall information work in context. Users are poorly supported in the initiation phase, as they recognize their information needs, especially with regard to resource awareness; in this context, interactive press-alerts are discussed. Some users (especially clinicians and patients) also require support in the interpretation of information, both satisfying themselves that the information is trustworthy and understanding what it means for a particular individua
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